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Mosquito protein may aid in controlling dengue virus infection | |
Scientists at the National University of Singapore (NUS) have identified a protein in Aedes aegypti mosquitoes, which could be instrumental in preventing and controlling dengue virus infections. Dengue virus, transmitted through the bite of infected Aedes aegypti mosquitoes, causes dengue fever in humans. In 2023, there were over 5 million reported cases of dengue fever worldwide. Currently, there is no specific treatment for dengue, and the only available vaccine, Dengvaxia, is for children who have been previously infected and live in dengue-endemic areas. The NUS researchers studied a pupal cuticle protein found in the exoskeleton of Aedes aegypti mosquitoes, revealing its structure and function. The pupal cuticle protein acts as a hard covering that supports and protects the mosquitoes’ bodies. The findings, published in Protein Science, suggest that this cuticle protein could be a potential target for developing innovative methods to control dengue virus infection. Professor J Sivaraman from the Department of Biological Sciences at NUS stated that the pupal cuticle protein could be a target for developing inhibitors or antibodies to control dengue virus infection. Understanding the molecular dynamics of mosquito-virus interactions could lead to novel antiviral strategies.  | |
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| Target State: New York Target City : New York City Last Update : Sep 13, 2025 2:54 AM Number of Views: 19 | Item Owner : medhealthinsight Contact Email: (None) Contact Phone: (None) |
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Hot-Web-Ads > Health & Beauty > Health Services > Item ID 13840926
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2025-09-13 (0.984 sec)