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Selank
Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. It increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test. Selank (0.01 mg/kg) decreases verticalization induced by apomorphine in mice. It also decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes when administered at a dose of 100 μg/kg. CAS No.: 129954-34-3 EC Number: 232-660-2 Melting point: 134-136 °C Density : 1.53±0.1 g/cm3(Predicted)

Target State: All States Target City : All Cities Last Update : Jul 16, 2025 2:33 AM Number of Views: 9	Item Owner : Shelley Contact Email: Contact Phone: +4407419376761

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Hot-Web-Ads > Shopping > Other Shopping Ads > Item ID 14164292

2025-07-16 (0.489 sec)